N | Inhibitor | ACh-current depression | ACh-current strength 15 min after the series, % | |
Rate of depression, %/min | Level of depression, % | |||
1 | No drugs; n = 11 | 4.55 ± 0.87 | 71.21 ± 0.62 | 95.58 ± 10.28 |
2 | DMSO, 0.1%, out; (Control); n = 10 | 4.97 ± 0.87 | 68.38 ± 1.92 | 95.68 ± 11.32 |
3 | СК-548, 50 µM + DMSO, 0.1%, out; n = 9 | 2.41 ± 0.79 | 85.34 ± 3.09*** | 103.2 ± 8.12 |
4 | СК-636, 50 µM + DMSO, 0.1%, out; n = 10 | 4.53 ± 0.80 | 43.93 ± 4.73***¯ | 38.41 ± 8.87*¯ |
5 | Wiskostatin, 5 µM + DMSO, 0.1%, out; n = 8 | 3.85 ± 2.13 | 54.18 ± 6.08***¯ | 36.63 ± 21.15*¯ |